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Unlocking the Power of IGF-1 LR3: A Comprehensive Guide

Introduction: IGF-1 LR3, or Insulin-Like Growth Factor 1 Long R3, is a synthetic analog of a naturally occurring peptide hormone. Renowned for its potent anabolic properties, IGF-1 LR3 has garnered attention in the fitness and bodybuilding communities for its potential to promote muscle growth, enhance recovery, and improve performance. In this comprehensive guide, we'll explore the mechanisms of action, benefits, risks, and practical considerations associated with IGF-1 LR3.

Understanding IGF-1 LR3:

IGF-1 LR3 is a modified form of insulin-like growth factor 1 (IGF-1), a peptide hormone produced primarily in the liver in response to growth hormone (GH) stimulation. The "LR3" designation refers to the addition of an extended amino acid sequence (Long R3) to the native IGF-1 molecule, increasing its half-life and bioavailability. This modification enhances the potency and duration of action of IGF-1 LR3 compared to its naturally occurring counterpart.

Mechanisms of Action:

IGF-1 LR3 exerts its effects primarily through binding to the IGF-1 receptor (IGF-1R) and activating downstream signaling pathways involved in cell growth, proliferation, and differentiation. Unlike other growth factors, IGF-1 LR3 exhibits increased binding affinity for the IGF-1R and is resistant to degradation by insulin-like growth factor-binding proteins (IGFBPs), resulting in prolonged biological activity.

Benefits of IGF-1 LR3:

  1. Muscle Growth: IGF-1 LR3 stimulates muscle hypertrophy by promoting protein synthesis, increasing satellite cell activation, and inhibiting protein breakdown. This results in accelerated muscle growth and improved muscle recovery following intense exercise.

  2. Enhanced Recovery: IGF-1 LR3 accelerates tissue repair and regeneration, making it particularly beneficial for athletes recovering from injuries or undergoing intense training regimens.

  3. Fat Loss: IGF-1 LR3 enhances lipolysis (breakdown of fat) and inhibits adipogenesis (formation of fat cells), leading to reductions in body fat percentage and improvements in body composition.

  4. Anti-Aging Properties: IGF-1 LR3 has been associated with various anti-aging effects, including improved skin elasticity, increased bone density, and enhanced cognitive function.

Risks and Considerations:

While IGF-1 LR3 offers significant potential benefits, it is not without risks. Common side effects associated with IGF-1 LR3 use include hypoglycemia (low blood sugar), joint pain, and fluid retention. Additionally, excessive or prolonged use of IGF-1 LR3 may increase the risk of insulin resistance and cardiovascular complications.

Dosage and Administration:

Due to its potency, IGF-1 LR3 should be used with caution and under the supervision of a qualified healthcare professional. Typical dosages range from 40mcg to 100mcg per day, administered via subcutaneous injection. Cycling protocols may vary depending on individual response and goals, with most users following a cycle of 6 to 8 weeks followed by a period of rest.


IGF-1 LR3 represents a powerful tool for individuals seeking to maximize their muscle growth, recovery, and performance. When used responsibly and in conjunction with a balanced diet and exercise regimen, IGF-1 LR3 can yield impressive results in terms of muscle hypertrophy, fat loss, and overall well-being. However, it is essential to understand the risks and potential side effects associated with IGF-1 LR3 use and to approach its administration with caution and prudence.

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ZPHC IGF-1 LR3, 5 vials, 0,2 mg/vial
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